Abstract: After billions years of nature selection, fishes have evolved excellent swimming ability. Studying their swimming mechanism helps a lot in improving the performance of modern undersea vehicle. To know how the sea eels swim, the biomimetic wave wing was simulated with IB-LBM in three-dimension space. Tianhe Ⅱ Supercomputer was employed to have the simulation accomplished with a mesh size of one hundred million. The unsteady movement of the sinusoidal wing in different amplitudes was simulated. And the vortex structure and force curves were obtained. The process how the unsteady vortices emerge and evolve were vividly depicted in the images. It turns out that IB-LBM works well when the boundary undergoes large deformation. Besides the advantages aforementioned, the details of flow field can also be available even in a large mesh size. In all, IB-LBM is widely employed in biomimetic simulations.