Abstract: To achieve a wide-velocity-range and large-space flight, the plane-symmetric configuration has been widely used for new spacecrafts. However, the lateral-directional coupling leads to serious flight instability. In this paper, the reason and significance of the lateral-directional coupling have been introduced, and a comprehensive verification scheme for coupling instabilities and new type control strategies was has been presented. By the aid of CFD-RBD simulation method, Dutch roll instability mode and lateral control instability mode have been demonstrated. Validity of new type control strategies has been proved through wind tunnel based virtual flight testing. Demands of control surface deflection angles can be reduced by more than 45% by applying new type control strategies.